Binding Characteristics to Mosquito-larval Midgut Proteins of the Cloned Domain II-III Fragment from the Bacillus thuringiensis Cry4Ba Toxin
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منابع مشابه
Binding characteristics to mosquito-larval midgut proteins of the cloned domain II-III fragment from the Bacillus thuringiensis Cry4Ba toxin.
Receptor binding plays an important role in determining host specificity of the Bacillus thuringiensis Cry delta-endotoxins. Mutations in domains II and III have suggested the participation of certain residues in receptor recognition and insect specificity. In the present study, we expressed the cloned domain II-III fragment of Cry4Ba and examined its binding characteristics to mosquito-larval ...
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Background Bacillus thuringiensis (Bt) toxin Cry4Ba specifically targets the mosquito larval midgut epithelial cells for its insecticidal toxicity. Prior to reaching the midgut cells, the toxin must penetrate the midgut peritrophic membrane (PM), an acellular gut protective structure lining the midgut epithelium. However, the mechanism of toxin passage through the PM is currently unknown. To ex...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2007
ISSN: 1976-6696
DOI: 10.5483/bmbrep.2007.40.5.783